Functional pituitary tumors cause different symptoms, based on the excess hormone they make. Here are symptoms of the most common functional pituitary tumors. Other, more rare, kinds of pituitary tumors may produce hormones such as prolactin and thyroid-stimulating hormone. And they may cause other symptoms. If you have any abnormal symptoms, see a doctor.
Pituitary tumors that make growth hormone (GH)
Symptoms caused by having too much GH are different in children than in adults. For children, symptoms include:
- Rapid growth
- Pain in joints
- Too much sweating
- Being abnormally tall (gigantism)
Over time, adults with tumors that cause high GH levels may have these symptoms:
- Increase in hat, shoe, or ring size caused by growth of head, hands, or feet
- Deeper voice
- Change in facial structure
- Tongue thickening
- Snoring or pauses in breathing while sleeping
- Joint pain
- Too much sweating
- Headaches
- Heart disease
- High blood sugar levels or diabetes
- High blood pressure
- Kidney stones
- Increased body hair growth
Pituitary tumors that make ACTH (corticotropin)
Pituitary tumors that make the hormone ACTH cause the adrenal glands to make too many steroid hormones. This is called Cushing disease and may lead to:
- Weight gain, often in the belly, chest, and face.
- Purple stretch marks on the belly and chest.
- A hump of fat on the back of the neck.
- Abnormal growth of body hair.
- A round, red, swollen face.
- Less interest in sex.
- Weak, brittle bones (osteoporosis).
- Acne.
- High blood pressure.
- High blood sugar levels.
- Irregular or absent menstrual periods.
- Headaches.
- Vision changes.
- Moodiness or depression.
- Easy bruising.
- Muscle weakness.